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Jang-Yang Chang Selected Research

BPR1K653

1/2011BPR1K653, a novel Aurora kinase inhibitor, exhibits potent anti-proliferative activity in MDR1 (P-gp170)-mediated multidrug-resistant cancer cells.

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Jang-Yang Chang Research Topics

Disease

96Neoplasms (Cancer)
05/2024 - 09/2002
21Squamous Cell Carcinoma of Head and Neck
11/2023 - 01/2014
16Head and Neck Neoplasms (Head and Neck Cancer)
01/2021 - 11/2011
14Carcinogenesis
11/2021 - 03/2009
9Neoplasm Metastasis (Metastasis)
05/2024 - 06/2010
9Mouth Neoplasms (Oral Cancer)
01/2022 - 02/2008
6Colorectal Neoplasms (Colorectal Cancer)
01/2021 - 01/2004
6Nasopharyngeal Carcinoma
12/2018 - 07/2002
5Lymphatic Metastasis
05/2020 - 12/2015
5Uterine Cervical Neoplasms (Cancer of the Cervix)
08/2016 - 01/2011
5Squamous Cell Carcinoma (Epidermoid Carcinoma)
11/2006 - 01/2004
4Peripheral Nervous System Diseases (PNS Diseases)
01/2022 - 01/2017
4Pancreatic Neoplasms (Pancreatic Cancer)
07/2016 - 03/2006
4Carcinoma (Carcinomatosis)
05/2015 - 07/2004
4Stomach Neoplasms (Stomach Cancer)
10/2013 - 01/2002
3Breast Neoplasms (Breast Cancer)
01/2020 - 12/2005
3Hypoxia (Hypoxemia)
03/2018 - 07/2013
3Leukemia
01/2018 - 01/2011
3Adenocarcinoma of Lung
01/2018 - 12/2010
3Genomic Instability
04/2010 - 03/2009
2COVID-19
01/2022 - 01/2021
2Cytokine Release Syndrome
01/2022 - 01/2021
2Prostatic Neoplasms (Prostate Cancer)
12/2021 - 01/2013
2Inflammation (Inflammations)
01/2018 - 10/2013
2Hyperalgesia
01/2017 - 10/2015
2Hypersensitivity (Allergy)
01/2016 - 01/2013
2Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
07/2014 - 07/2006
2Lung Neoplasms (Lung Cancer)
12/2010 - 07/2006
2Hepatocellular Carcinoma (Hepatoma)
12/2009 - 11/2006
2Ataxia Telangiectasia (Louis Bar Syndrome)
02/2008 - 01/2007
2Neutropenia
03/2006 - 01/2002
2Febrile Neutropenia
03/2006 - 01/2002

Drug/Important Bio-Agent (IBA)

13Cisplatin (Platino)FDA LinkGeneric
01/2022 - 01/2002
10Proteins (Proteins, Gene)FDA Link
01/2021 - 11/2007
9Paclitaxel (Taxol)FDA LinkGeneric
01/2022 - 07/2009
9Biomarkers (Surrogate Marker)IBA
12/2021 - 06/2012
8DNA (Deoxyribonucleic Acid)IBA
08/2019 - 11/2003
7cathepsin SIBA
05/2024 - 06/2010
7Messenger RNA (mRNA)IBA
12/2021 - 04/2010
7Oxaliplatin (Eloxatin)FDA LinkGeneric
01/2021 - 05/2006
7TubulinIBA
01/2019 - 07/2009
6Small Interfering RNA (siRNA)IBA
12/2017 - 04/2010
5PlatinumIBA
11/2023 - 06/2012
5Type II DNA Topoisomerases (Topoisomerase II)IBA
12/2021 - 11/2003
5MicroRNAs (MicroRNA)IBA
11/2021 - 01/2014
5SurvivinIBA
01/2020 - 07/2009
5Aurora KinasesIBA
08/2014 - 03/2009
5Fluorouracil (Carac)FDA LinkGeneric
04/2013 - 01/2002
5Leucovorin (Folinic Acid)FDA Link
12/2011 - 01/2002
4Cysteine Proteases (Cysteine Protease)IBA
05/2024 - 04/2012
4CarcinogensIBA
01/2021 - 04/2010
4IntegrinsIBA
03/2020 - 12/2015
4GemcitabineFDA Link
12/2011 - 01/2006
4Antineoplastic Agents (Antineoplastics)IBA
01/2007 - 07/2002
3CalciumIBA
01/2022 - 01/2017
3Arecoline (Arecolin)IBA
01/2021 - 04/2010
3EnzymesIBA
04/2020 - 09/2015
3Carmustine (FIVB)FDA Link
12/2018 - 11/2007
3MPT0B098IBA
03/2018 - 07/2013
32,5- bis(5- hydroxymethyl- 2- selenienyl)- 3- hydroxymethyl- N- methylpyrroleIBA
10/2011 - 01/2007
3CaspasesIBA
04/2010 - 07/2004
2Cetuximab (Erbitux)FDA Link
11/2023 - 01/2019
2Transforming Growth Factors (Transforming Growth Factor)IBA
02/2023 - 06/2020
2Neuroprotective AgentsIBA
01/2022 - 01/2017
2PoisonsIBA
12/2021 - 12/2017
2Etoposide (VP 16)FDA LinkGeneric
12/2021 - 02/2008
2Transcription Factors (Transcription Factor)IBA
01/2021 - 12/2016
2NucleotidesIBA
01/2021 - 10/2008
2Fibronectins (Fibronectin)IBA
06/2020 - 10/2017
2betaglycan (TGFBR3)IBA
05/2020 - 05/2016
2IronIBA
04/2020 - 08/2016
2Hormones (Hormone)IBA
01/2020 - 01/2017
2TamoxifenFDA LinkGeneric
01/2020 - 11/2007
2MethyltransferasesIBA
12/2018 - 11/2007
2CytokinesIBA
01/2018 - 01/2013
2Therapeutic UsesIBA
01/2018 - 07/2009
2ErbB Receptors (EGF Receptor)IBA
10/2017 - 06/2013
2Penicillamine (Cuprimine)FDA Link
08/2016 - 05/2015
2Insulin-Like Growth Factor Binding Protein 3IBA
05/2016 - 12/2015
2Insulin-Like PeptidesIBA
05/2016 - 12/2015
2STAT3 Transcription Factor (Signal Transducer and Activator of Transcription 3)IBA
01/2016 - 12/2010
2Vinorelbine (Navelbine)FDA LinkGeneric
07/2014 - 01/2006
2Histone Deacetylase 6IBA
05/2014 - 07/2013
2Interleukin-6 (Interleukin 6)IBA
10/2013 - 12/2010
2Peroxisome Proliferator-Activated Receptors (PPAR)IBA
05/2013 - 02/2008
26- methoxy- 3- (3',4',5'- trimethoxybenzoyl)- 1H- indoleIBA
07/2009 - 07/2004
2trioctyl phosphine oxide (TOPO)IBA
02/2008 - 11/2003
2Thalidomide (Thalomid)FDA Link
11/2006 - 01/2004
2Docetaxel (Taxotere)FDA Link
09/2005 - 01/2002
2TriterpenesIBA
02/2005 - 01/2004
22,5- bis(4- hydroxy- 3- methoxybenzylidene)cyclopentanoneIBA
07/2004 - 06/2003
2Antimitotic AgentsIBA
07/2004 - 01/2004
1AlpelisibIBA
11/2023

Therapy/Procedure

17Therapeutics
11/2023 - 01/2004
14Drug Therapy (Chemotherapy)
11/2023 - 03/2010
4Oral Hygiene (Dental Hygiene)
01/2019 - 10/2013
2Neoadjuvant Therapy
01/2019 - 10/2008
2Immunotherapy
12/2017 - 08/2016
2Chemoradiotherapy
07/2014 - 12/2011
2Radiotherapy
01/2011 - 01/2004